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meet zandawala

Meet Zandawala

Assistant Professor

Summary

Our research group is interested in context-dependent modulation of behaviors and physiological processes by neuropeptides and their G-protein coupled receptors.

The nervous systems of animals utilize a wide variety of chemicals for neuronal communication. These include amino acids, biogenic amines, and neuropeptides amongst others. Neuropeptides are by far the most diverse, and control a range of essential physiological processes including feeding, metabolism, sleep, stress, reproduction, development and locomotion. Our working group is interested in understanding how neuropeptides mediate their effects in the fruit fly Drosophila melanogaster. We utilize multiple approaches in our lab including standard molecular techniques, CRISPR/Cas9, Drosophila genetics, behavioral analyses, optogenetics and calcium imaging. We are also developing cutting-edge genetic tools to study neuropeptide function in Drosophila.

Publications

Journals

2024

eLife

Martina Held, Rituja S. Bisen, Meet Zandawala, Alexander S. Chockley, Isabella S. Balles, Selina Hilpert, Sander Liessem, Federico Cascino-Milani and Jan M. Ache

2024

Journal of Experimental Biology

Marishia Agard, Meet Zandawala and Jean-Paul Paluzzi

2024

eLife

Jayati Gera, Marishia Agard, Hannah Nave, Farwa Sajadi, Leena Thorat, Shu Kondo, Dick R. Nässel, Jean-Paul V. Paluzzi and Meet Zandawala

This important study provides a comprehensive analysis of ITP neuropeptide and its role as an anti-diuretic and metabolic hormone in the fruit fly Drosophila....

2024

Nature

Sven Dorkenwald, Arie Matsliah, Amy R. Sterling, Philipp Schlegel, Szi-chieh Yu, Claire E. McKellar, Albert Lin, Marta Costa, Katharina Eichler, Yijie Yin, Will Silversmith, Casey Schneider-Mizell, Chris S. Jordan, Derrick Brittain, Akhilesh Halageri, Kai Kuehner, Oluwaseun Ogedengbe, Ryan Morey, Jay Gager, Krzysztof Kruk, Eric Perlman, Runzhe Yang, David Deutsch, Doug Bland, Marissa Sorek, Ran Lu, Thomas Macrina, Kisuk Lee, J. Alexander Bae, Shang Mu, Barak Nehoran, Eric Mitchell, Sergiy Popovy

2024

General and Comparative Endocrinology

Meet Zandawala, Muhammad Bilal Amir, Joel Shin, Won Cheol Yim and Luis Alfonso Yáñez-Guerra

2024

European Journal of Neuroscience

Benedikt Hofbauer, Meet Zandawala, Nils Reinhard, Dirk Rieger, Christian Werner, Jan Felix Evers and Christian Wegener

2024

Nature

Philipp Schlegel, Yijie Yin, Alexander S. Bates, Sven Dorkenwald, Katharina Eichler, Paul Brooks, Daniel S. Han, Marina Gkantia, Marcia dos Santos, Eva J. Munnelly, Griffin Badalamente, Laia Serratosa Capdevila, Varun A. Sane, Alexandra M. C. Fragniere, Ladann Kiassat, Markus W. Pleijzier, Tomke Stürner, Imaan F. M. Tamimi, Christopher R. Dunne, Irene Salgarella, Alexandre Javier, Siqi Fang, Eric Perlman, Tom Kazimiers, Sridhar R. Jagannathan, Arie Matsliah, Amy R. Sterling, Szi-chieh Yu, Claire

2023

Journal of Comparative Neurology

Giulia Manoli, Meet Zandawala, Taishi Yoshii and Charlotte Helfrich-Förster

2023

Genome Biology and Evolution, Volume 15, Issue 7, July 2023, evad108

Luis Alfonso Yañez Guerra and Meet Zandawala

2022

BMC Biol (2022). 20(1) 187

Nayeli Escudero Castelán, Dean C. Semmens, Luis Alfonso Yañez Guerra, Meet Zandawala, Mario dos Reis, Susan E. Slade, James H. Scrivens, Cleidiane G. Zampronio, Alexandra M. Jones, Olivier Mirabeau and Maurice R. Elphick

2021

PLOS Genetics (2021). 17(3) 1–31

Meet Zandawala, Thomas Nguyen, Marta Balanyà Segura, Helena A. D. Johard, Mirjam Amcoff, Christian Wegener, Jean-Paul Paluzzi and Dick R. Nässel

2018

Cellular and Molecular Life Sciences (2018). 75(6) 1099–1115.

Meet Zandawala, Richard Marley, Shireen A. Davies and Dick R. Nässel

2017

Open Biology 7(9) 170129

Meet Zandawala, Ismail Moghul, Luis Alfonso Yañez Guerra, Jérôme Delroisse, Nikara Abylkassimova, Andrew F. Hugall, Timothy D. O'Hara and Maurice R. Elphick

2017

in PLOS Genetics (2018). 14(11) 1–31

Meet Zandawala, Maria E. Yurgel, Michael J. Texada, Sifang Liao, Kim F. Rewitz, Alex C. Keene and Dick R. Nässel

Reviews

2024

Molecular and Cellular Endocrinology

Meet Zandawala and Jayati Gera

This review focuses on the unpaired family of proteins in Drosophila which are evolutionarily related to mammalian leptin and the cytokine interleukin 6....

2022

Open Biol (2022). 12(7) 220174.

Dick R. Nässel and Meet Zandawala

2020

Cell and Tissue Research 382

Dick R. Nässel and Meet Zandawala

2019

Neuroscience (2019). 13 1262

Dick R. Nässel, Meet Zandawala, Tsuyoshi Kawada and Honoo Satake

2018

General and comparative endocrinology (2018). 264 64–77

Meet Zandawala, Shi Tian and Maurice R. Elphick